Acuros™

Acuros™

Acuros is Transpire’s next generation radiotherapy dose calculation software. Through the novel application of Transpire’s leading edge numerical methods, Acuros will provide an unprecedented combination of speed, accuracy, and precision; advancing the state-of-the-art in radiotherapy treatment planning and improving overall quality of care.

Unlike approximate methods in clinical use, Acuros calculates dose by directly solving the governing transport equations. Acuros accurately accounts for all relevant neutral and charged particle interactions, without the use of pre-calculated kernels or empirical corrections. Acuros and Monte Carlo solve the same equations through different methods (Acuros-deterministically, Monte Carlo-stochastically), and the accuracy of both are comparable.

Acuros combines the accuracy of Monte Carlo with the speed of approximate methods. Acuros is free of statistical noise, enabling the effects of small treatment planning perturbations to be accurately and rapidly assessed. Acuros also offers an unrivaled spatial precision, where millimeter resolution can be locally realized at critical areas such as in build-up regions or near heterogeneities, without significantly increasing dose calculation times.

Dose field comparison between Attila and Monte Carlo (EGSnrc) along a line through the patient anatomy. Dose obtained using image derived material properties. Build-up regions and peaks accurately resolved by Attila.

Dose field calculated by Attila for a 6 MV photon beam treatment. Work funded by NCI Grant 1 R43 CA105806-01A1.

Comparison between Attila and MCNPX for a tungsten shielded brachytherapy applicator. MCNPX calculation performed by M.D. Anderson Cancer Center.

Dose contours on critical structures for a tandem and ovoid brachytherapy treatment.